Error: Couldn't open config file "awstats.mysite.conf" nor "awstats.conf" after searching in path ".,/etc/awstats,/usr/local/etc/awstats,/etc,/etc/opt/awstats": No such file or directory

- Did you use correct config parameter ?
Example: If your config file is awstats.mysite.conf, use -config=mysite - Did you create your config file 'awstats.mysite.conf' ?
If not, you can run "./../../tools/awstats_configure.pl" from command line, or create it manually.

Check config file, permissions and AWStats documentation (in 'docs' directory).