Brookville was settled in 1796 by Moses Knapp. Attracted to the area by its abundant lumber and other natural resources, Knapp built a gristmill and a log house at the confluence of Sandy Lick and Mill Creeks. The settlement grew at a steady pace over years, and was designated as the county seat of Jefferson County in 1830. Lumber became the predominant industry, bringing in more settlers and spurring the growth of the town. By the late 19th century, Brookville was a thriving town with a variety of prosperous businesses and industries. Brookville still maintains that industrious spirit, and continues to grow and prosper to ensure a strong and vital community for future generations.
The 90-acre Historic District is a collection of nearly 300 buildings, residential and commercial alike, constructed between 1830 and 1930 and listed in the National Register of Historic Places. A self-guided walking tour is a favorite among visitors. Information is available from merchants on Main Street.